1.      What does the Doctor say to Macbeth about Lady Macbeth’s condition? What is Macbeth’s reaction?

2.      What is the Doctor referring to when he says, “Therein the patient Must minister to himself?”

3.      What does the Messenger tell Macbeth he sees coming toward Dunsinane? How does Macbeth respond?

4.      What does Macbeth say to Macduff about his mortality? What is Macduff’s response? How does Macbeth react?

5.      Describe Macbeth’s reaction to Lady Macbeth’s death. Compare his reaction to the reaction he had after the murder of Duncan.

6.      Elaborate on the importance of the scene when Lady Macbeth says, “Out damned spot! out, I say! One; two. Why then ’tis time to do’t. Hell is murky. Fie, my lord, fie! a soldier, and afeard? What need we fear who knows it, when none can call our pow’r to accompt? Yet who would have thought the old man to have had so much blood in him?” This scene illustrates a change in the character of Lady Macbeth?